Glycyrrhiza glabra

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COMMON NAME

Common ivy, English ivy, European ivy Standardized: licorice
Other: Russian licorice, Spanish licorice, Turkish licorice.

INTRODUCTION

Licorice root is one of the most widely used medicinal herbs worldwide. It was used by the Egyptians as a flavoring for a drink called Mai-sus. Dioscides, when traveling with Alexander the Great, recommended that his troops carry and use licorice to help with stamina for long marches, as well as for thirst in areas of drought. In the Middle Ages it was taken to alleviate the negative effects of highly spicy or overcooked food. It was also used for flavoring tobacco, and as a foaming agent in fire extinguishers and beer. In a recent survey of Western medical herbalists, licorice ranked as the 10th most important herb used in clinical practice.

CONSTITUENTS

Glycyrrhizin, complex immune-stimulant sugars.

Herbions’ Specification

Scientific Name: Glycyrrhiza glabra

Active:     Glycyrrhizin

Part used: Roots

Assay: NLT 1.5% by HPTLC and 4.0% by HPLC

Biological Activity

Anti-inflammatory, GIT protective agent, sweetening agent.

Glycyrrhizin has also demonstrated antiviral, antimicrobial, anti-inflammatory, hepatoprotective, and blood pressure-increasing effects in vitro and in vivo, as is supported by the finding that intravenous glycyrrhizin (as if it is given orally very little of the original drug makes it into circulation) slows  the Liquorice has also demonstrated efficacy in treating inflammation-induced skin hyperpigmentation. Liquorice may also be useful in preventing neurodegenerative disorders and dental caries.

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On which biologically active substance (BAS)/active ingredient, Herbion extracts are standardized?

Glycyrrhiza glabra extract is standardized on glycyrrhizin, Tribulus terrestris extract is on furostanol saponin, while Hedera helix extract is on hederacoside C.

What is the percentage of BAS in our products?

Glycyrrhizin should not be less than 4% in Glycyrrhiza glabra powder extract, furostanol saponin should not be less than 40 % in Tribulus terrestris powder extract and hederacoside C should not be less than 10 % in Hedera helix powder extract.

Which grade of extraction solvents did you used?

Pharmaceutical grade.

What is the result of residual solvent analysis?

Residual solvent meets specification of EP.

What is the GRAS status of your products?

All the material (herbs and solvents) used are all generally recognized as safe, hence our products are also obey all regulation required for GRAS status.

What is the GMO (Genetically Modified Organism) status of your products?

These product are not manufactured from GM (Genetically Modified) raw materials and are therefore not subject to labelling under any regulations.

What is the BSE/TSE (Bovine Spongiform Encephalopathy/Transmissible Spongiform Encephalopathy) status of your products?

During the course of extract manufacturing and packaging, these products did not come into contact with any materials, which could be derived from TSE/BSE risk materials. Hence it is BSE/TSE free.

What is the ETO (Ethylene oxide) status of your products?

By residual solvent analysis as per EP, we ascertain that ETO should be within limit.

Does your product is gluten free?

Yes, our products are gluten free and can be test as per requirement.

What is your modus operandi for the collection of herbs?

We collect the herbs our self or procure them from the certified supplier.

Do you have effective mechanism for the identification of right herb?

Yes, we have experience and expert botanists for the identification of right herb. They maintain reference herb library, and reference herbarium sheets.  Even we have our own herbal Garden.

Does collected herbs are pesticides free?

Yes, our extract comply the pesticide testing as per requirement of USP (United States Pharmacopeia).

Does your products are heavy metal free?

Yes, our extract comply the heavy metal testing as per requirement of EP.

Does your products are irradiated?

These products, whole or in part, has not been subjected to Ionizing Radiation.

Did your facility is GMP compliances?

Yes, our facility is GMP compliance.

What certification do you have?

We are GMP certified firm from the ministry of health of Pakistan, Ukraine, and Moldova. We also hold ISO 9001:2015, ISO 14001:2004, ISO 22000:2008, HACCAP and HILAL certificates.

Does your product is spiked with any synthetic pharmaceuticals?

No, our product is 100% pure natural extracts.

Can you provide us the consistent supply?

Yes, we are bulk manufacturer of natural herbal extracts.

What are the intended use of your extracts?

Our extract are for pharmaceutical industries, cosmetic industries, and FMCG.

What is special about Herbion Extract?

Our extract are for pharmaceutical industries, cosmetic industries, and FMCG.

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